Lovegra vs Addyi (Flibanserin): What Is More Effective for Women?

Indian Lovegra in a Few Words

female Lovegra

How does it function?

The action of female Lovegra in physiological aspect is based on the impact of PDE5 inhibitor that helps to increase the level of blood circulation in vascular system of female pelvic organs. Active action of nitrogen oxide expands smooth muscle cells of arteries and fills the labia and clitoris with a large amount of blood. Moreover, a woman feels an increase in the functionality of mucous glands starting a strong lubrication process in vagina. Breasts plump up and become firm and elastic; there is a perceptible blush on cheeks, and a woman feels the rush of strength and energy. Then the level of arousal starts to increase and there is an urgent need for sexual contact. Lovegra is the best way to combat sexual dysfunction in the representatives of the beautiful half of humanity.

Application method

The action of Lovegra begins within 30-40 minutes after administration and lasts up to 5-6 hours. Daily dose must not exceed 100 mg of active ingredient (1 tablet per day). If necessary, a lady can reduce the dose to 25 mg (if there are a number of contraindications or some side-effects were experienced) or increase it to 150 mg (if the effect has minimal manifestation). Tablets are taken orally and drunk with a glass of water. It is not recommended to use Lovegra along with alcohol and fatty, salty, spicy or overly sweet food. The dosage of Lovegra must not be exceeded without particular necessity or prior consultation by a specialist. Self-medication and uncontrolled use of the medicine are prohibited.

Indications for use

Lovegra is prescribed to those women who have the following conditions:

  • regular manifestations of sexual dysfunction in the body;
  • prolonged experience of orgasmic disorders;
  • complete or partial impairment of  sexual attraction to a man;
  • malfunction of reproductive or genitourinary systems;
  • dissatisfaction with sexual relations with a partner;
  • absence of sexual drive and desire to initiate sex;
  • inflammation, acute soreness or severe dryness in vaginal opening;
  • short sexual intercourse;
  • constant irritation, apathy, drowsiness;
  • nervous or stressful state;
  • complete absence of pleasant sensations when orgasm is achieved;
  • a negative reaction to sexual arousal.

Before starting to use the drug, it is advisable to undergo a clinical examination by an attending physician.

Composition

Lovegra is produced in India in the form of tablets that have the shape of a diamond and are covered with a safe red coating. One blister contains 4 tablets of Lovegra. The active substance making a woman’s reproductive system work is sildenafil citrate. This component is found in tablets equivalent to 100 milligrams of sildenafil. In the meantime, Lovegra consists of the following substances: calcium hydrogenphosphate, crystalline cellulose, sodium carmellose, magnesium stearate, lactose and triacetin. The use of all elements is safe and clinically proven.

Contraindications

Pregnant and lactating women are not allowed to take Lovegra. The results or its use in these cases can be the most deplorable. Treatment with Lovegra can cause significant harm to an undeveloped fetus and cause genetic abnormalities. If you do not want to harm your child, it is recommended to refuse Lovegra application for this period.

Lovegra should be taken with caution by those patients who have renal and hepatic diseases, cancer, heart disease, low or high blood pressure, peptic ulcer and anatomical deformations of vagina. Also, the drug is contraindicated to children and girls who have not reached adulthood. Usually it is not prescribed to patients who are completely contraindicated to have sexual activity for any reason. Viagra is contraindicated to women who are currently taking nitrogen oxide donors. To exclude the possibility of an acute form of side-effects, a lady should conduct an additional sensitivity analysis to the medicinal substances added to the drug.

Possible side-effects

Before passing the course of treatment with this drug, a woman should undergo a qualified examination by her attending doctor. In order to avoid the occurrence of adverse side-effects from the use of Lovegra, a specialist must identify the patient’s individual intolerability to any component of the drug, including sildenafil citrate.

Overdose

Lovegra was subjected to various experiments and studies resulting from which it was found out that the drug is indicative to women having severe sexual disorders. To date, the remedy continues to be tested. Cases of an overdose of Lovegra were not identified. However, with occurrence of the slightest symptoms of side-effects, a woman should immediately stop taking the medication, if possible, rinse the stomach with a weak solution of potassium permanganate and contact a medical center. Self-medication and subsequent application of tablets are strictly prohibited. Incorrect or untimely treatment can lead to development of more serious diseases.

Flibanserin Summary

Addyi (flibanserin)

Addyi development

The drug Addyi (flibanserin) was officially launched in the United States. This means that all women with a hypoactive disorder of sexual desire are able to adjust their sex life by means of this magic remedy. The Food and Drug Administration (FDA) approved the production of Addyi with only the fourth attempt. Sprout Pharmaceuticals Inc. was trying to launch a project to produce flibanserin back in 2010, but at that time the effect of the drug was not clinically proven.

And then the pharmacists went to the trick. Along with the best marketers, they launched the campaign with the slogan proclaiming that there are twenty-six official drugs for male impotency, whereas there are none of them for female sexual disorders. The motto “26-0 in favor of men” allowed the producers of flibanserin to exert pressure on the public. Masterfully having played a card of sexual discrimination of women, Sprout Pharmaceuticals Inc received powerful support from various legal organizations. After numerous petitions and lobbying of politicians on this issue the production of the drug was approved from the fourth attempt.

How does flibanserin work?

In order to understand the way this drug works, first it is important to find out the meaning of a hypoactive disorder of sexual desire. So, if the incomprehensible scientific terminology is avoided, low sexual desire of a woman is the result of a malfunction or imbalance in the production of hormones and mediators. Sexual function requires a complex interaction of several neurotransmitters and hormones, both centrally and peripherally. Sexual desire is considered as a result of a complex balance between suppressive and stimulating signals in cerebrum. For example, the hormones dopamine, estrogen, progesterone and testosterone play an exciting role, while prolactin and serotonin act as inhibitors (or suppressors).

Flibanserin is a multifunctional agonist-antagonist of serotonin capable of restoring sexual desire by affecting the prefrontal cortex of brain. Therefore, flibanserin acts by increasing the level of neurotransmitters dopamine and norepinephrine in the prefrontal cortex, and by reducing the action of serotonin.

Was flibanserin ever tested?

Since the first attempts to start the project, the company Sprout Pharmaceuticals Inc conducted a large-scale, randomized, placebo-controlled trials that involved 2400 women of pre- and post- menopause (average age was 36 years). Women who took 100 mg of flibanserin reported a slight increase in sexual desire. At the same time, according to the results in the North American group of volunteers, the number of ‘sexually satisfying cases’ increased from 2,7 to 4,6 during the test period, as opposed to placebo . These data were enough to convince the FDA that Addyi is indeed effective, despite the side-effects among which the most common were nausea, dizziness, fatigue, drowsiness, insomnia, dry mouth, hypotension, low blood pressure and even loss of consciousness during orgasm. The latter effect was particularly pronounced when the drug was administered with alcohol.

Despite the numerous critical opinions, flibanserin is set into production. However, by the decision of the FDA, Sprout Pharmaceuticals Inc is required to conduct a study to further assess health risks associated with the interaction of flibanserin with alcohol. In the United States, the drug is available for women only after prescription from certified health professionals and certified pharmacies depending on the availability of health insurance.

What does a woman feel after Addyi application?

The effective dosage of flibanserin is 100 mg. Administration is carried out within a month once a day before bedtime. When taking female Viagra, dopamine is released in blood, and the level of estrogen and testosterone elevates which results in increase of sexual activity and attraction. Under the action of the drug blood circulation in genital area increases and blood flow into pelvic organs gets enhanced resulting in impact on sensory nerves located in erogenous zones. These nerve endings transmit impulses to spinal cord and brain faster and stronger. Producers assure that regular intake of the drug contributes to the development of vaginal secretion that allows a woman to reach a bright and strong orgasm.

Is It Possible to Put a Sign of Equality between Lovegra and Addyi (Flibanserin)?

First of all, the drugs are based on different active substances that affect diverse mechanisms in female body to ensure sexual drive. This is a critical discrepancy that is allows never put the equality mark between Lovegra and Addyi. These active substances cause difference side-effects and have particular contraindications.

Moreover, many experts are skeptical about the very definition of the drugs as “female Viagra”. Associate Professor of the University of Victoria in British Columbia believes that sexual problems of women during the menopause are less physiologically-oriented than men’s ones. Frigidity is caused by external factors, such as interpersonal relationships, necessity to make social decisions, pressure associated with characteristics of female sexuality, inferiority complexes, stress at work, etc. And it would be rather reckless to argue that the influence of all these factors can be leveled by taking one pill.

No diagnostic test has revealed any biological links between brain-hormone-genital blood stream in women’s sexual problems. Low sexual desire in women reflects the difference in desire between the two partners, and it is unethical and unscientific to associate the differences in the couple’s desires solely with hormone deficiency in a woman during menopause. Viagra relieves men of erectile dysfunction short-term – this is a proven fact. However, there is no evidence that flibanserin or sildenafil is an antidote to lowered libido in women, since sexual desire is a more complex and amorphous condition than the mechanism of erection.