What is Cialis Soft Tabs? The Fullest Pharmacy Guide

Cialis Soft Tabs: What is Cialis Soft Tabs, How Does The Drug Work, The Most Common Side Effects, Contraindications & Drug Interactions, Original Cialis Or Generic Cialis

Product Overview
What is Cialis Soft Tabs? The Fullest Pharmacy Guide
Name:
Cialis Soft Tabs
Other Names:
Tadalafil
Active ingredient:
Tadalafil
Dosages (mg):
20
Drug Class:
Phosphodiesterase type 5 (PDE5)
Indications:
Erectile Dysfunction and Benign Prostate Hyperplasia treatment
Strength
20 mg
Quantity
10 pills
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Cialis Soft Tabs is a powerful, long-lasting and quick-acting drug belonging to the class of medicines called PDE5 inhibitors. PDE5 inhibitors have been in market launch in 1998 in the form of Viagra (active ingredient: sildenafil). Medications belonging to the group of PDE5 inhibitors can be used for erectile dysfunction and pulmonary hypertension. The first PDE5 inhibitor ever to enter the market was the active ingredient sildenafil under the trade name Viagra. Other known PDE5 inhibitors are Cialis Soft Tabs (active ingredient: tadalafil), Levitra (active ingredient: vardenafil) and Spedra (active ingredient: avanafil).

What is Cialis Soft Tabs?

Cialis represents a patented development existing since 2003. In addition to Cialis Original you can also find his generic drugs, which differ in their composition and mode of action of the original in fact. The active substance is tadalafil. Thanks to this substance, Cialis and Cialis generics exerts such an exquisite effect. Tadalafil improves erection without the required effect in the absence of sexual stimulation.

The characteristic feature of Cialis lies in its fast and lasting effect. First results start in 20 minutes after use and take about 36 hours! If you are planning an eventful weekend, Cialis is the best option. The onset of effect varies for each user. Much depends on individual characteristics of the organism, the dosage and the dosage form. Individual peculiarities can only be recognized when taking them. The dosage of 20 mg is almost always optimal and is rarely changed. But there are different forms of medicines. After use of the tablet form, the first results are expected in 40-60 minutes at the earliest.

When you buy Cialis Soft Tabs, you get a remedy that is almost completely identical to the original. But their price is at least one third lower than the price of the original. You can also find generic Cialis in different dosage forms: tablets, soft tabs (or chewable tablets) or a fruity gel. For example, Cialis Original or Generic are made in tablet form and start working in 40-60 minutes. They are taken like all other tablets with water.

Cialis Soft is something completely different. This has a form of chewable tablets that dissolve in the mouth. Tadalafil is absorbed through the oral mucosa. The active substance succeeds earlier in the blood and begins to act earlier. The required effect occurs about twice faster, i. about 30 minutes after use. Cialis Soft is perfect for parties because it can be combined with sensible amounts of alcohol.

It is not recommended to take supplements with the medications that promote vasodilation to exceed the permissible dose. In the two cases, it is 20 mg, which corresponds to one tablet. As a rule, tadalafil is easily tolerated. In some cases, headaches, nasal congestion and facial flushing may occur.

The effectiveness of tadalafil has been confirmed in several large clinical studies. In its analysis, it was determined that the frequency of successful sexual acts after using tadalafil in the dose of 20 mg is 92%. In the groups where subjects used the control preparation, this value was a maximum of 34%. The improvement in the erection quality due to the use of Cialis in the above dosages recorded 71 and 84% of the subjects. The investigations carried out have demonstrated the readiness of this drug and its conformity with the characteristics of the ideal preparation for the treatment of ED. They were first described in 1998: efficacy, safety, rapid onset of action, long duration of action and the ability to combine with food and alcohol. You can be sure that the effect will delight you as it lasts 24-36 hours. Can you imagine that you cannot worry about potency problems for more than 24 hours?

Cialis Soft Tabs: How Does The Drug Work?

Although the active ingredients of the power resources differ in detail from each other, but in principle all PDE5 inhibitors act in the same way. Originally, PDE5 inhibitors were only intended to treat pulmonary arterial hypertension disease. During development, however, they have been found to have a primarily positive effect on man's erectile function. A detail that brings the manufacturer billions of dollars to date.

Cialis Soft Tabs How Does The Drug Work

What happens during and after ingestion in the body? Why do the active substances improve our ability to achieve erection? As the name suggests, PDE5 inhibitors inhibit the enzyme phosphodiesterase5. This enzyme is responsible for the degradation of the two messengers cGMA (cyclic adenosine monophosphate) and cGMP (cyclic guanosine monophosphate). In particular, cGMP is essential in an erection because the messenger is activated by nitric oxide and leads to an expansion of the blood vessels. Since the enzyme that degrades cGMP is inhibited, the concentration of cGMP thus increases automatically. An erection becomes more likely.

It is important that phosphodiesterase5 inhibition does not occur everywhere in the body. The enzyme is found mainly in the corpus cavernosum of the penis and in the lungs. It is therefore not surprising that PDE5 inhibitors are mainly used for erectile dysfunction and pulmonary hypertension. In the latter disease, there is an increased blood pressure in the pulmonary circulation. An expansion of the blood vessels means in practice that more blood can flow into the penis in less time. In addition, the blood is prevented from draining. The erection thus remains longer and arises more easily. In addition, we would like to point out that PDE5 inhibitors only facilitate erectile function. You do not get up the penis - as many people think - on autopilot. There is still a sexual stimulus needed to get an erection at all. PDE5 inhibitors are a supportive measure.

Which Are The Most Common Side Effects Of Cialis Soft Tabs?

Cialis Soft Tabs is generally well tolerated. Compared to other PDE5 inhibitors, it has a more selective effect on its target enzyme PDE5 and hardly on other enzymes, e.g. PDE-6, an enzyme in the retina that plays an important role in visual vision. Due to this specificity, the side effects of Cialis Soft Tabs are lower. Disturbances of color vision, which can occur when using other PDE5 inhibitors, have sometimes not yet occurred in Cialis Soft Tabs.

As with all medicines, side effects may still occur. As a rule, however, they are only mild to moderate and do not occur in everyone. Only about 10 percent of users report side effects.

Common side effects include headache, pain in the back, arms and legs, flushing, nasal congestion, indigestion, and acid regurgitation. ‘Common’ refers to side effects that have occurred in one to ten out of every 100 patients.

Side effects have occurred in one to ten out of every 1,000 patients. In the case of Cialis Soft Tabs this includes dizziness, abdominal pain, blurred vision, nosebleeds, eye pain, increased sweating, difficulty breathing, accelerated heartbeat or tachycardia, high or low blood pressure or tinnitus.

Side effects that have occurred in one to ten out of every 10,000 patients are considered rare. These include swelling of the eyelids, red eyes, sudden deafness or deafness, temporary memory loss, fainting, seizures or hives.

Special caution should be exercised when taking Cialis Soft Tabs in conjunction with other medicines. For example, concomitant use with vasodilating nitrates or alpha-blockers results in a mutual enhancement of the effect, so that the side effects can also be significantly increased. It can lead to a strong drop in blood pressure, impaired blood clotting or increased heart rate. Therefore, it is important to talk to the doctor about taking the medicine beforehand. In addition, it should be noted that Cialis Soft Tabs should not be taken in conjunction with grapefruit juice, as it will prevent the release of tadalafil and possibly increase side effects.

Cialis Soft Tabs Contraindications & Drug Interactions

  • Cialis Soft Tabs should not be used in patients with known hypersensitivity to tadalafil or any of the excipients.

In clinical trials, tadalafil has been shown to potentiate the hypotensive effects of nitrates and other NO donors. This is attributed to a joint effect of nitrates or other NO donors and tadalafil on nitric oxide / cGMP metabolism. Consequently, Cialis Soft Tabs is contraindicated in patients using organic nitrates in any form. Likewise, a co-medication with molsidomine is contraindicated. Patients should also be clearly informed that they must not use illegally purchased nitrates, called ‘poppers’ (amyl nitrite), or any other nitrates while taking Cialis Soft Tabs. Cialis Soft Tabs should not be combined with guanylate cyclase (such as riociguat) stimulants due to an additive hypotensive effect.

  • Cialis Soft Tabs is contraindicated in severe hepatic impairment (Child-Pugh C).

Sexual activity poses a potential risk to patients with pre-existing cardiovascular disease. Therefore, treatment with Cialis Soft Tabs is not recommended in men who have severe heart disease and are therefore advised against sexual activity.

The following patient groups with cardiovascular disease were not included in clinical trials:

  • Patients with heart attack during the previous 90 days
  • Patients with unstable angina or angina pectoris that occurred during sexual activity
  • Patients with heart failure (NYHA II or higher) during the last 6 months
  • Patients with uncontrolled arrhythmias, hypotension (<90/50 mm Hg) or uncontrolled hypertension
  • Patients with a stroke during the previous 6 months

The clarification of erectile dysfunction should include the identification of possible underlying causes. After appropriate medical diagnosis, appropriate treatment should be established. Before initiating therapy for benign prostatic hyperplasia with tadalafil, other causes of the condition, and in particular prostate cancer, should be excluded by differential diagnosis. Before starting therapy and at regular intervals during therapy, the patient should be digitally examined rectally and, if necessary, the prostate-specific antigen (PSA) should be determined.

Guanylate cyclase stimulators (such as riociguat), as well as PDE5 inhibitors, induce changes in intracellular cGMP. Despite different mechanisms of action, both substance classes have a vasodilatory effect. If cGMP levels rise when combined with both agents, an additive effect on systemic blood pressure with increased risk of symptomatic hypotension is expected. Cialis Soft Tabs must therefore not be co-administered with guanylate cyclase stimulants.

In patients taking alpha1 receptor blockers, concomitant administration of tadalafil may lead to symptomatic hypotension. The combination of tadalafil and doxazosin is not recommended. There are limited clinical data on the safety of Cialis Soft Tabs given a single dose in patients with severe hepatic insufficiency (Child-Pugh class C). Once-daily use of tadalafil has not been studied in patients with hepatic insufficiency and is not recommended in severe hepatic impairment. In patients with mild to moderate hepatic impairment, the prescribing physician should perform a careful, individual risk-benefit assessment.

There are limited clinical data on the tolerability of Cialis Soft Tabs in patients with severe renal insufficiency (creatinine clearance ≤30 ml / min). Due to the increased bioavailability (AUC) of tadalafil, limited clinical experience, and the inability to increase clearance by dialysis, daily administration of Cialis Soft Tabs is not recommended in patients with severe renal impairment.

Caution should be exercised when Cialis Soft Tabs is prescribed to patients taking potent CYP3A4 inhibitors (ritonavir, saquinavir, ketoconazole, itraconazole and erythromycin), as increased tadalafil exposure (AUC) has been observed when used in combination with these medicinal products).

Priapism has been reported with the use of PDE5 inhibitors. Patients with erections lasting more than 4 hours are advised to seek medical attention. Failure to treat priapism immediately can result in penile tissue damage and permanent loss of potency. Cialis Soft Tabs should be used with caution in patients with priapism-predisposing conditions (e.g., sickle cell anemia, multiple myeloma, or leukemia) or in patients with anatomical penile deformation (e.g., deviation, corpora cavernosa fibrosis, or Peyronie's disease).

The safety and efficacy of combining Cialis Soft Tabs with other PDE5 inhibitors or erectile dysfunction treatments has not been studied. Therefore, the use of such combinations is not recommended. It is not known if Cialis Soft Tabs is effective in patients with spinal cord injury or other neurological disorders. Cialis Soft Tabs contains lactose monohydrate. Patients with rare hereditary problems of galactose intolerance, lactase deficiency or glucose-galactose malabsorption should not take this medicine.

As explained below, interaction studies with 10 mg and / or 20 mg tadalafil were performed. Concerning such interaction studies, where only the 10 mg tadalafil dosage was used, clinically relevant interactions at higher doses cannot be completely ruled out.

Original Cialis Or Generic Cialis: Where Is The Difference?

Original Viagra was the first remedy to treat erectile dysfunction (ED). In the present, you can also find other potency-enhancing supplements on the market. Although there are a large number of variants, Levitra and Cialis take a respected place alongside Viagra. At the end of 2017, after the expiry of the patent for Cialis (tadalafil), many generics appeared in pharmacies, providing more favorable alternatives for the treatment of ED. As soon as low-priced alternatives to improve potency had been put up for sale, men had questions about their particularities, advantages and disadvantages.